This refers to individuals currently experiencing illness caused by a microorganism that exhibits resistance to multiple antibiotics or antimicrobial agents. This resistance complicates treatment, as standard medications are ineffective in eradicating the infection. For example, a patient with pneumonia caused by a strain of Klebsiella pneumoniae resistant to carbapenems would fall under this category.
The presence of such infections represents a significant public health challenge. Treatment options are often limited, leading to increased morbidity, mortality, and healthcare costs. Historically, the overuse and misuse of antibiotics have contributed to the rise and spread of these resistant organisms, underscoring the need for improved antimicrobial stewardship and infection control practices.
